March 2, 2021

Today, the Consortium of Independent Immunology Clinics (CIIC) announces the publication of Validation of inducible basophil biomarkers: Time, temperature and transportation by Wiley Periodicals LLC on behalf of The Official Journal of the International Clinical Cytometry Society.

This publication on the topic of Clinical Cytometry provides an overview of research conducted by multiple CIIC providers and their peers; Henry Li, Mark Scarupa, Richard L. Wasserman, Athena Economides, Carla Ward, Douglas Jones, James Tracy, James Friedlander, Zachary Jacobs, Donald McNeil and Oral Alpan. 

Link to Publication

Background:

The short stability window of several hours from blood collection to measuring basophil activation has limited the use of flow cytometry-based basophil activation assays in clinical settings. We examine if it is possible to extend this window to 1 day allowing for shipment of samples between laboratories. Several options exist for reporting the results including reporting all the measured values directly, calculating ratios and reporting a single value covering all measured results. Each of these options have different stability and value to the physician.

About the CIIC

The CIIC is a professional medical organization formed in 2013 and comprised of select Board Certified Immunologists in private practice throughout the USA. We provide high quality care for patients with Primary Immune Deficiency Disorders (PIDD), promote access to treatment, serve as advocates to patients and physicians who care for PIDD patients and participate in research that benefits patient care.

CIIC Mission – Provide cutting edge therapy to patients with Primary Immune Deficiency